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Python Web & API Frameworks: Django, FastAPI, Flask & More

Python web and API frameworks — full-stack, micro and async — with links to documentation and notes on project activity.

28 topics•4 categories•Updated October 2026

Full-stack Frameworks

7 entries

Batteries-included frameworks with ORMs, auth and admin.

01DjangoHigh-level web framework that encourages rapid development and clean design; documentation is at docs.djangoproject.com. 02Django documentationOfficial Django docs, including release notes for the current version. 03Django REST frameworkToolkit for building web APIs on Django. 04Django NinjaFast, type-hint-based API framework for Django. 05Web2pyFull-stack framework with a web-based IDE; its GitHub repository was last updated in October 2026. 06TurboGearsFramework that starts as a micro framework and scales up; its GitHub repository was last updated in October 2026. 07MasoniteModern, developer-centric framework; last GitHub update June 2026.

Micro & API Frameworks

8 entries

Lightweight frameworks for services and APIs.

08FlaskLightweight WSGI web application framework; the link now points to the stable docs instead of the old 2.0 version. 09FastAPIHigh-performance API framework based on Starlette and Pydantic, using Python type hints. 10LitestarASGI framework for APIs with built-in data validation and dependency injection. 11FalconMinimalist framework for reliable APIs and microservices. 12BottleFast, simple single-file WSGI micro framework. 13PyramidFlexible framework that scales from small to large applications. 14CherryPyMinimalist object-oriented web framework. 15PycnicJSON API framework "for lazy people"; the project is small and its site is plain http.

Async & ASGI Frameworks

6 entries

Frameworks and toolkits built on asyncio.

16StarletteLightweight ASGI toolkit that underlies FastAPI; the old starlette.io address did not respond. 17UvicornASGI server for Python web frameworks. 18TornadoWeb framework and asynchronous networking library. 19SanicAsync framework designed for fast HTTP responses; the link now goes to the project site instead of a Full Stack Python page. 20aiohttpAsync HTTP client and server framework. 21QuartAsync re-implementation of the Flask API.

Related Pages

7 entries

Neighbouring pages on this site.

22PythonPython hub. 23Python FrameworksPython web and application frameworks. 24Python Libraries for Web DevelopmentLibraries around web apps. 25Microservices Frameworks for PythonPython microservices frameworks. 26API Management Platforms and GatewaysAPI management platforms. 27Software FrameworksFrameworks by language. 28Python Frameworks for AIAI frameworks for Python.

Frequently Asked Questions

What are the main Python web frameworks?

Django is the leading full-stack framework, Flask and Pyramid are flexible micro and mid-size frameworks, and FastAPI, Litestar and Starlette are modern async frameworks for APIs.

Which should I choose?

Choose Django for content and data-driven sites with an admin, FastAPI or Litestar for typed async APIs, and Flask for small services where you want to pick your own components.

What is the difference between WSGI and ASGI?

WSGI is the older synchronous interface for Python web apps, while ASGI supports async code, WebSockets and long-lived connections. Starlette, FastAPI, Litestar, Sanic and Quart are ASGI-based.

Why were some links changed?

The Flask link pointed to the old 2.0 docs, Bottle moved to its docs site, and the Sanic entry linked to a third-party page; each now points to the project's own current documentation.

How current is this page?

Links were checked in October 2026. Sites that block automated checks are kept and may need a manual click. Last-commit dates are from GitHub in October 2026 and show activity only; check each project's release notes before adopting it.