13 Leading LLM Gateway Platforms

A curated tour of the gateways and proxies that sit between your application and model providers — one OpenAI-compatible API, with routing, fallbacks, caching, budgets and usage tracking. LLM gateways focus on model traffic; for broader control over LLM, MCP and agent traffic, see the AI Gateways page. Every listing has been checked for a live, working destination.

Open-Source & Self-Hosted LLM Gateways

5 Platforms
  1. LiteLLM

    Open-source AI gateway and LLM proxy putting 140+ providers and 1,800+ models behind one OpenAI-compatible key, with spend tracking, smart routing, and self-hosting anywhere, even air-gapped.

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  2. Bifrost

    Open-source (Apache 2.0), self-hostable AI gateway unifying 1,000+ models across 8+ providers behind a drop-in OpenAI/Anthropic-compatible SDK — with provider failover, budgeting, MCP gateway support, and built-in observability.

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  3. Otari (Mozilla.ai)

    Open-source, OpenAI-compatible LLM gateway you run yourself, built on Mozilla.ai’s any-llm, with virtual keys, budgets and usage tracking across 40+ providers; a hosted option adds routing, observability and team management.

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  4. LLM Gateway

    Open-source (AGPLv3), self-hostable unified API for 40+ LLM providers with real-time cost analytics, automatic failover, and drop-in OpenAI SDK compatibility; bring-your-own-keys tier is free.

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  5. MLflow AI Gateway

    Gateway built into the open-source MLflow AI platform, exposing an OpenAI-compatible endpoint for any LLM provider with native tracing, evaluation, and MCP server access management, licensed Apache 2.0.

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Managed & Hosted LLM Gateways

5 Platforms
  1. OpenRouter

    Unified interface for 400+ models across 70+ providers, letting developers find the best model and price for any prompt with automatic fallback and edge-optimized routing.

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  2. Cloudflare AI Gateway

    Intelligent control plane for AI applications offering dynamic model routing, response caching, usage analytics, and unified billing across providers, built on Cloudflare's global network.

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  3. Vercel AI Gateway

    One endpoint for hundreds of AI models from Vercel, without managing separate rate limits and API keys for each provider.

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  4. Requesty

    OpenAI-compatible router for 600+ models, with smart routing, caching, failover, observability and EU data residency.

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  5. Portkey

    LLM gateway with routing, guardrails, observability and governance, available as open-source and hosted. Palo Alto Networks completed its acquisition in May 2026.

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Secure & Compliance-Focused LLM Gateways

1 Platform
  1. SUPERWISE Sentinel

    Commercial LLM gateway that redacts PII and secrets from every request inside your own network before the prompt reaches a public LLM, for teams with data-protection and compliance requirements.

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LLM Routing & Cost-Optimization Frameworks

2 Platforms
  1. RouteLLM

    Open-source framework for serving and evaluating LLM routers, which send easy queries to cheaper models to cut costs without losing quality.

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  2. vLLM Semantic Router

    Programmable mixture-of-models router from the vLLM project that picks the right model for each request across heterogeneous LLM inference.

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